Crinetics is a pharmaceutical company based in San Diego, California that develops much-needed therapies for people with rare endocrine diseases. We were founded by a dedicated team of scientists with the simple belief that better therapies developed from rigorous innovation can lead to better lives. Our work continues to make a real difference in the lives of patients. We have a prolific discovery engine and robust pipeline across preclinical and clinical development. We are driven by science with a patient-centric and team-oriented culture. This is an exciting time to join Crinetics as we shape our organization into the world’s premier fully integrated endocrine company from discovery to patients. Come join our team as we transform the lives of others.

 

The Director of Discovery toxicology will be accountable for timely delivery of effective nonclinical safety support to drug discovery and development programs teams from target selection through to early development. Drive the application of state-of-the-art technologies (in silico, in vitro), to support nonclinical safety assessment in the selection of novel drug targets and to develop detailed discovery toxicology screening strategies/plans, de-risking and safety risk mitigation strategies to deliver molecules to development with desirable nonclinical safety profiles and low risk of clinical failure due to toxicity. Actively participate on project/program/product teams, build strong engaging, collaborative partnerships with drug discovery teams and provide input to senior management to drive and influence decisions that impact toxicology/safety strategic initiatives aimed at building a strong early drug discovery pipeline and reduce attrition (post NME GLP toxicology and clinical development).

 

You will be part of the Global Nonclinical Safety Sciences team that delivers end-to-end support to small molecule & biotherapeutics drug discovery and development at Ferring. You are expected to work in a highly collaborative team environment, playing a pivotal role in shaping the nonclinical safety profile of targets/molecules of our early drug discovery programs through effective project leadership, experience as a discovery toxicologist and a “problem solver”.

 

 

Requirements:

 

Physical Activities: On a continuous basis, sit at desk for a long period of time; intermittently answer telephone and write or use a keyboard to communicate through written means. Some walking and lifting up to 25 lbs. may be required. The noise level in the work environment is typically low to moderate. The physical demands described above are representative of those that must be met by an employee to successfully perform the essential functions and responsibilities of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions and responsibilities:

 

Laboratory Activities (if applicable): Biology and chemical laboratory environment experience needed. Environmental health and safety requirements also apply.

 

You may be required to travel for up to 5% of your time.

 

In addition to your base pay, our total rewards program consists of a discretionary annual target bonus, stock options, ESPP, and 401k match. We also provide top-notch health insurance plans for employees (and their families) to include medical, dental, vision and basic life insurance, 20 days of PTO, 10 paid holidays, and a winter company shutdown.

 

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience and education. Crinetics Pharmaceuticals is a multi-state employer, and this salary range may not reflect positions that work in other states. Your recruiter can share more about the specific salary range during the hiring process.

 

Crinetics is proud to be an Equal Opportunity Employer. We provide equal employment opportunities to all employees and employment applicants without regard to unlawful considerations of sex, sexual orientation, gender (including gender identity and/or expression), pregnancy, race, color, creed, national or ethnic origin, citizenship status, religion or similar philosophical beliefs, disability, marital and civil union status, age, genetic information, veteran status or any personal attribute or characteristic that is protected by applicable local, state or federal laws

Vaccination requirement:
Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, Crinetics requires that all employees and contractors be fully vaccinated and have received the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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